Postdoctoral Researcher (Bioinformatics / Computational Biology) (m/f/d)
Bioinformatics
full-time
limited
Research, Other professions
Campus Benjamin Franklin, Steglitz
Berlin
Working at Charité
Shape the future of precision oncology with us.
At Charité – Universitätsmedizin Berlin, one of Europe's leading academic medical centers, you will join an internationally recognized research environment at the interface of Spatial Biology, Single-Cell Technologies, Artificial Intelligence, and Translational Surgery. Working alongside bioinformaticians, clinicians, surgeons, pathologists, and molecular biologists, you will help develop the next generation of diagnostic and therapeutic strategies for pancreatic cancer.
Benefit from cutting-edge technologies, unique clinical cohorts, international collaborations, and the opportunity to contribute your own scientific ideas while helping shape the future of precision oncology.
Overview of the position
Become part of a newly established, internationally oriented translational research platform at Charité that combines Spatial Biology, Single-Cell Technologies, Artificial Intelligence, and Precision Oncology to address fundamental questions in pancreatic cancer biology and translate discoveries into clinical applications.
- Analyze and integrate high-dimensional multi-omics datasets, including spatial transcriptomics, single-cell/single-nucleus RNA sequencing, imaging, and clinical datasets, to identify novel biomarkers, molecular pathways, and therapeutic targets.
- Develop innovative bioinformatics workflows and AI-driven analytical pipelines to investigate the tumor microenvironment, cellular plasticity, metastasis, and mechanisms of therapy resistance, and validate findings across large international datasets and clinical cohorts.
- Collaborate within an interdisciplinary and internationally connected team of bioinformaticians, surgeons, pathologists, molecular biologists, and data scientists, contributing to high-impact publications and large collaborative research consortia, including PrepAIred, LIMPACT, and PERCEPTION.
- Play a key role in establishing an internationally visible translational research platform at the interface of Bioinformatics, Spatial Biology, Artificial Intelligence, and Precision Oncology, with the opportunity to develop your own scientific ideas, establish international collaborations, and strengthen your academic profile through high-impact publications and competitive grant applications.
- You will be employed as a scientific researcher. In accordance with §110 (4), sentence 3 of the Berlin Higher Education Act (BerlHG), appropriate working time will be allocated to support your own scientific qualification and career development.
What we are looking for
- A completed university degree and PhD in Bioinformatics, Computational Biology, Data Science, Medical Informatics, or a related discipline.
- Extensive experience in the analysis of spatial transcriptomics and single-cell/single-nucleus RNA sequencing datasets, with a strong interest in translational cancer research.
- Excellent programming skills in R and/or Python, as well as experience in developing and implementing bioinformatics analysis pipelines.
- Ideally, experience integrating multimodal datasets and a background in tumor biology, oncology, or immunology, with enthusiasm for working in interdisciplinary and international research environments.
- Excellent written and spoken English and the ambition to further develop your scientific career within an innovative and internationally visible research program...
Charité offers you
- An exciting and highly independent position at one of Europe's leading academic medical centers within an internationally recognized research environment.
- The opportunity to join a newly established, internationally visible translational research group with substantial scientific freedom and outstanding career development opportunities.
- Access to state-of-the-art Spatial Multi-Omics technologies, including Atera, Xenium, Visium HD, CosMx, single-cell and single-nucleus sequencing, as well as cutting-edge AI-driven computational approaches.
- Close collaboration with internationally leading research institutions, including MD Anderson Cancer Center, University of North Carolina, New York University, and partners of the German Pancreatic Cancer Alliance (GPCA).
- Outstanding opportunities for scientific development through high-impact publications, international conference participation, establishment of independent research projects, and competitive grant applications.
- An outstanding translational research environment with direct interaction between computational scientists, experimental researchers, and clinicians, enabling rapid translation from molecular discovery to clinical application.
- Flexible working hours, 30 days of annual leave, occupational pension scheme (VBL), comprehensive training and professional development opportunities, as well as a wide range of health and sports programs.
- Excellent scientific infrastructure and close integration with the Berlin Institute of Health (BIH), the Max Delbrück Center (MDC), and other leading research institutions within Berlin's vibrant biomedical research ecosystem.
Information regarding the position
- Paygrade XXX according to TVöD VKA-K. Your job grade depends on your job qualification whereas the experience level depends on the number of working years. The yearly gross salary is hereby provided based on a full time position excluding yearly bonus and additional pay. You may find further information here
- Full-time job with 38.5 hours per week
- The position is limited until 31.08.2029, as it is tied to the project duration
- 30 days of paid vacation per year
- The application period ends on 13.08.2026
- Position ID 7766
If you have questions, please contact:
PD Dr. med. Alexander Semaan
Leitender Oberarzt
Klinik für Allgemein-, Viszeral-, Thorax- und Gefäßchirurgie
Charité – Universitätsmedizin Berlin
Campus Benjamin Franklin