Senior Clinical Genomics Scientist (d/w/m)
full-time
limited
Medical faculty, Research
BIH Berlin Mitte, Campus Virchow-Klinikum, Wedding
Berlin Institute of Health
Working at Charité
The Berlin Institute of Health at Charité (BIH) is dedicated to biomedical translation. Its mission is to translate research findings into personalized prevention, diagnostics, and therapies to benefit patients and provide the scientific community with effective tools. With approximately 750 employees, the BIH specializes in translational method development, precision medicine, regenerative therapies, and biomedical data science. Closely integrated with Charité, the BIH promotes excellent research and facilitates the accelerated transfer of new discoveries into clinical practice through its supporting platforms and programs. Through these efforts, the BIH builds strong partnerships and fosters innovation-driven medicine in both national and international contexts.
At the Berlin Institute of Health at Charité (BIH), the Spatial Diagnostics Platform (led by Dr. Dr. René Hägerling and Dr. Oliver Klein) is emerging as a novel platform for next-generation diagnostics. We combine state-of-the-art genomics, new sequencing technologies, spatial omics, bioinformatics, and clinical expertise to make complex molecular data usable for precision medicine. A particular focus is on spatially guided sequencing: the targeted integration of spatial tissue information with molecular genetic analysis to better understand molecular findings within their biological and clinical context. The goal is to develop new diagnostic approaches for patients with rare diseases, oncological conditions, and complex molecular disease patterns, and to translate these into clinically relevant applications.
We are seeking an experienced professional who not only evaluates molecular genetic findings but also wishes to help shape new diagnostic approaches and workflows—a specialist in human genetics. The position is to be filled as soon as possible on a fixed-term basis through December 31, 2029, on a full-time basis (40 hours per week).
What you expect
- Medical, molecular genetic, and scientific interpretation of complex genomic datasets.
- Interpretation of genetic data in the context of rare diseases, oncology, and complex genomic alterations.
- Development, implementation, and refinement of diagnostic analysis and interpretation processes for whole-genome sequencing and new sequencing technologies.
- Development of innovative diagnostic approaches for long-read sequencing, novel sequencing methods - including SbX-based approaches -, liquid biopsy, somatic mosaic disorders, and spatially guided sequencing.
- Quality assurance, validation, and benchmarking of new methods against established diagnostic standards.
- Translating scientific findings into robust, clinically applicable workflows within the Spatial Diagnostics Platform.
- Close collaboration with experts in human genetics, pathology, oncology, bioinformatics, data science, IT, and clinical disciplines.
What bring you along
- A university degree with excellent grades (state examination or equivalent) in human medicine or a related field
- Successfully completed specialty training in human genetics or comparable medical training, or several years of experience in molecular genetic analysis
- A completed doctoral degree in the natural sciences or medicine is desirable
- In-depth knowledge of human genetics, molecular oncology, genomics, molecular pathology, or a closely related field
- Experience in the analysis and interpretation of NGS data, ideally in the field of whole-genome sequencing, is an asset.
- Expertise in one or more of the following areas: long-read sequencing, analysis of structural variants and complex genomic alterations, liquid biopsy, diagnosis of mosaic disorders or rare diseases, molecular tumor diagnostics, or spatially guided sequencing.
- A good understanding of diagnostic quality, validation, benchmarking, and reproducible analysis processes is desirable
- A strong ability to interpret complex molecular findings from both clinical and scientific perspectives is an asset.
- Excellent oral and written communication skills in German and English, as required to perform the duties of the position.
- You are characterized by a structured, responsible, and team-oriented approach to work.
What we offer
A key role in building a forward-looking platform for precision diagnostics, as well as opportunities to shape the direction of the field in central areas of clinical genomic interpretation and platform development. The opportunity to actively help shape new genomic and spatially resolved diagnostic methods. Work at the intersection of genomics, spatially/imaging-guided sequencing, clinical interpretation, and translational research. Access to state-of-the-art sequencing and spatial omics technologies, including Axelios I technology.
- A varied job in a forward-looking research institute
- Pay group Ä2 TV-Ä clinical staff. The classification is based on qualifications, the respective experience level is calculated on the basis of professional experience. The annual salary (gross) is stated for a full-time position without special or additional payments. The collective agreement can be found here.
- Additional benefits customary in the public sector (including annual special payment, company pension scheme (VBL), capital-forming benefits)
- Flexible working hours and the option of working remote
- 30 vacation days per year (with a five-day week)
Various support offers to balance work and family life (childcare, cooperation with voiio) - Training and further education opportunities
- Mobile citizens' office on site
- Corporate benefits (travel, leisure, shopping, etc.), Wellhub, JobRad
- Very easily accessible and attractive workplace at the Rahel Hirsch Center for Translational Medicine, Luisenstr. 65, 10117 Berlin and Campus Virchow-Klinikum, Föhrer Str. 15, 13353 Berlin
We live diversit!
We welcome applications from people with diverse backgrounds, regardless of gender, nationality, ethnic and social origin, religion and ideology, disability, age, sexual orientation and identity. Applications from women are expressly encouraged. Severely disabled and equivalent applicants will be given special consideration if they have the same qualifications and suitability.
We believe that diverse teams representing a wide range of experiences, perspectives and backgrounds enrich our research and work.
Please submit your application via our online application form with a letter of motivation, curriculum vitae (without photo, without age statement and without information about your marital status) and other relevant attachments (such as employer references, degree certificates, etc.) until 20.08.2026 under ID 7773.
Note: If you have a foreign degree, please submit proof of recognition of your degree in Germany with your application. The proof can be obtained via the anabin database. Please note that it may be necessary to obtain a certificate assessment from the ZAB. You can find more information here.
Proof of measles immunity / measles vaccination is a prerequisite for employment for those born after 1970.
You can find more information about BIH here.
Contact persons
For technical or role-related questions regarding the job posting, please contact Mr Dr. Dr. René Hägerling (Email: rene.hägerling@bih-charite.de) and Dr. Oliver Klein (Emai: oliver.klein@bih-charite.de).
For questions regarding the application process, please contact Denise Bornschein by email at jobs@bih-charite.de
We are looking forward to your application!